LAURA H. CYPHERS

A vaccine against respiratory syncytial virus (RSV) was effective at preventing RSV-associated illness among older adults and the children of vaccinated mothers, based on interim results from 2 phase 3 trials. If licensed, the vaccine, an intramuscular injection that contains a combination of prefusion F glycoproteins from RSV A and B, would be the first available for RSV.
Source: JAMA Online First

After authorizing Makena, a hydroxyprogesterone caproate injection, under an accelerated approval pathway in 2011, the US Food and Drug Administration (FDA) has pulled approval for the drug. “[T]he touchstone of FDA drug approval is a favorable benefit-risk assessment,” FDA Commissioner Robert M. Califf, MD, said in a statement. “[W]ithout that favorable assessment, the drug should not have the status of being FDA-approved.”
Source: JAMA Online First

Revised COVID-19 vaccination recommendations reflect the impact of circulating Omicron variants as well as current population immunity due to previous infection and vaccination, according to a statement from the Strategic Advisory Group of Experts on Immunization (SAGE), part of the World Health Organization (WHO).
Source: JAMA Online First

This Medical News article discusses a recent court ruling that invalidated the Affordable Care Act’s requirement for privately insured patients to have no out-of-pocket costs for certain preventive services and drugs.
Source: JAMA Online First

This Medical News article discusses whether hormonal fluctuations and calcitonin gene-related peptide, or CGRP, may cause migraines in some women.
Source: JAMA Online First

Each night, approximately 580 000 people in the US experience homelessness; 40% do so in unsheltered settings (eg, encampments, vehicles, abandoned buildings). Black, Indigenous, and Latinx Americans are impacted disproportionately. Many people experiencing homelessness eschew shelter due to concerns about restrictive rules, safety and privacy, and the inability to keep belongings, pets, and partners. In many regions, there are long wait lists for shelters. Despite this, in response to concerns about people living in public spaces, government employees conduct involuntary displacement of homeless encampments in which they forcibly move those living in encampments, throw out belongings, and arrest those who refuse. Although displacements may involve offers of shelter or, less commonly, housing, most result in scattering to other unsheltered places. Local governments justify forced displacements based on concerns about health and safety, complaints of housed residents, and the need to enforce laws against sleeping in public. Occasionally, involuntary displacements garner significant media attention and protest, as happened with the recent displacement of residents of McPherson Square in Washington, DC. However, more often they occur without interest or attention.
Source: JAMA Online First

This modeling study examines the potential long-term health effects of involuntary displacement among unsheltered people experiencing homelessness who inject drugs in 23 US cities.
Source: JAMA Online First

This Viewpoint discusses the continuum of preventive, community, and institutional services necessary for improving care for people with mental illness experiencing homelessness.
Source: JAMA Online First

This Arts and Medicine feature excerpts a chapter from The Covenant of Water, the new novel from Abraham Verghese, which follows the lives of a family in South India over the 20th century who have a “condition” that consigns at least 1 member per generation to death by drowning.
Source: JAMA Online First

This JAMA Insights Clinical Update discusses the management of early pregnancy loss, including expectant, medical, and surgical management regimens.
Source: JAMA Online First