This Medical News article discusses the discovery of a mechanism that may protect against venous blood clots during long periods of immobility.
Source: JAMA Online First

In this narrative medicine essay, a family physician writes to her deceased aunt about how their shared genetics connects their histories through which she hopes to create a future unavailable to her aunt in the 1970s.
Source: JAMA Online First

This Viewpoint outlines the progress made toward eliminating hepatitis B and C but emphasizes the work that remains to prioritize diagnosis and treatment of populations disproportionately affected by viral hepatitis, including ensuring that there are systems in place to treat those infected and care for those at risk.
Source: JAMA Online First

This Viewpoint discusses the expansion of politically motivated informed consent laws and identifies opportunities for the medical profession to challenge them.
Source: JAMA Online First

This clinical trial compares the efficacy of 2 different doses of VE303, a defined bacterial consortium of 8 strains of commensal Clostridia, and placebo in preventing recurrence of Clostridioides difficile infection among adults at high risk.
Source: JAMA Online First

A 95-year-old farmer taking prednisolone for bullous pemphigoid had 24 hours of abdominal pain, 2 weeks of diarrhea, and 3 months of intermittent abdominal bloating and anorexia. Evaluation showed purpuric macules and small thumbprint-like patches on her upper abdomen and central chest and a white blood cell count of 13 600/μL (89.9% neutrophils, 0.2% eosinophils). What is the diagnosis and what would you do next?
Source: JAMA Online First

This JAMA Patient Page describes the autosomal dominant genetic disorder of Marfan syndrome and its diagnosis and treatment.
Source: JAMA Online First

In this narrative medicine essay, an ophthalmology resident parses out the inherent bias of family history and urges clinicians to dig deeply to uncover family health histories of those who have limited access.
Source: JAMA Online First

This Viewpoint details how and why improved oversight of private equity acquisition of physician practices and hospitals is needed to mitigate the effects on health care costs, clinicians’ jobs, and patients’ access to care.
Source: JAMA Online First

This Viewpoint discusses how and why cross-market hospital mergers are different than prototypical within-market mergers in their effects on patients and communities, why the trend may be accelerating, and future policy and research directions.
Source: JAMA Online First