Despite numerous advances in perioperative care, surgical site infection (SSI) remains a frequent complication after major abdominal surgery, with gastrointestinal procedures among the highest risk for infection. Besides the increased length of stay and overall costs of care, SSIs are the most common indication for readmission after surgery. Antimicrobial prophylaxis given during the perioperative period is an essential, evidence-based aspect of SSI prevention. The choice of prophylactic regimen in patients undergoing a surgical procedure should include an agent effective against the most likely infecting organisms.
Source: JAMA Online First